Brain Stack Microdose Mushroom Capsules

Nootropic adaptogens, superfoods, and vitamins plus mushroom magic for memory and focus

4.8 29 reviews
DescriptionBenefitsHow to UseIngredients

1–4 caps a day keep stress and brain fog away.

Brain Stack is proactive and reactive brain health. Our clinically-studied formula combats the effects of stress at its source to support calm alertness, speedy processing, memory, mood, and mental adaptability. Our refined take on the Stamets microdose formula improves functional brain connectivity and supports healthy serotonin activity to alleviate the cognitive, emotional, and psychological manifestations of stress.

When the stress response activates, all 5 ingredients help to nourish the brain and protect from oxidative stress. Then Sage comes in to help the brain cope with stress and reduce irritability. As stress continues, energy gets depleted. Vitamin B3 helps convert fat, carbs, and protein into cellular energy/ATP. Prolonged periods of stress can impact cognition and mood. Psilocybin and Lion's Mane improve functional brain connectivity, while Cinnamon improves memory and energy metabolism.

Commit to Brain Stack and you should start to see transformational results in 4 weeks.

25mg Psilocybe cubensis per capsule

Clinically studied to help:*
  • promote calm alertness and concentration
  • promote mental stamina and clarity
  • improve learning and memory function
  • support speedy processing
  • reduce physical, mental and emotional fatigue
  • boost energy and mood
  • protect from oxidative stress
  • control stress-related weight gain
  • promote healthy blood flow
  • relieve anxiety and depression
  • improve sleep quality
  • stimulate neurogenesis, the growth of new nerve cells from your own stem cells
  • enhance neuroplasticity, your nervous system’s ability to reorganize your nerve pathways
  • amplify synaptoplasticity, making new synaptic connections by encouraging them to connect with nearby nerve cells
  • reverse or slow cognitive aging processes

If you wish to follow the Paul Stamets protocol, take 1–4 caps together for 4 consecutive days. Follow this by 3 days without a microdose. Repeat.

Because Brain Stack contains Niacin, which promotes metabolism and energy production, it's recommended that you take them in the morning.

You are not confined to this method. Refer to the image gallery for other popular microdosing schedules, or this article for a comprehensive guide to microdosing.

Brain Stack is not designed as a way to consume large amounts of psilocybin.

+ Organic Psilocybe Cubensis: Studied to be neuroprotective, promote neurogenesis and synaptogenesis, and improve global functional brain connectivity impaired by stress, diet, and lack of sleep. Activates serotonin receptors responsible for mood and memory consolidation.

+ Organic Lion's Mane: Known to be neuroprotective, improve cognition, and increase the release of Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF), key molecules involved in plastic changes related to learning and memory. Studied to enhance sleep quality and mood.

+ Organic Sage: Rich in terpenes and phenolics shown to improve memory and attention in low doses and elevate mood, increase alertness, calmness, and contentedness in high doses.

+ Organic Cinnamon: Shown to reduce oxidation and inflammation in the brain and improve memory, increase attention, and enhance cognitive processing.

+ Naturally-derived Niacin: Addresses Vitamin B3 deficiencies essential for cognition, energy production, and cellular protection.


Rewire yourself.

You're boldly going after success and you're looking for natural, safe ways to help yourself along the way.

Lately, you've been using the Paul Stamets microdosing protocol with the Brain Stack Microdose Capsules. You've noticed yourself sharper and more aware during the day, calmer and more relaxed in stressful situations. You're watching yourself rise above your former self, as though you've completely rewired your own inner workings.

Life is full of unknowns.

Our products aren't. If you have any questions, we’re here: [email protected].

100% Natural Icon 100% Natural
100% Plant-Sourced Icon 100% Plant-Sourced
Fully Recyclable Packaging 100% Recyclable
Contaminant-Free Contaminant Free
Cruelty-Free Icon Cruelty-Free
Gluten-Free Icon Gluten-Free
Keto-Friendly Icon Keto-Friendly
Locally Grown Organic Mushrooms Locally Grown Organic Mushrooms
No Additives Icon No Additives
No Preservatives Icon No Preservatives
Non-GMO Icon Non-GMO
Nut-Free Icon Nut-Free
Sugar-Free Icon Sugar-Free
Vegan Icon Vegan

Brain Health 101.

Optimal brain function hinges on the remarkably precise interconnections made among millions of neurons. Stress, diet, depression, poor sleep, and environmental toxins impair functional brain connectivity, which can impact your mood, memory, focus, processing, energy, and motor skills.

Optimal Cognition Around the Clock.

Brain Stack is proactive and reactive brain support. Five clinically-studied ingredients promote the brain's ability to cope with stress and recover from it by restoring functional brain connectivity and healthy serotonin activity, while helping protect it from inflammation and oxidative stress.

Anatomy of Brain Stack.

Psilocybin brings clarity and mental adaptability by activating serotonin receptors and inducing rapid changes in brain connectivity. Niacin improves energy levels, while Lion's Mane delivers nutrients to stimulate brain cell growth and improve cellular health. Cinnamon and Sage promote calm alertness while protecting your brain from oxidative stress and inflammation.

Intelligent Neurotransmitter Recycling System.

Psilocybin and Lion's Mane stimulate healthy serotonin, dopamine, and norepinephrine activity and BDNF (brain-derived neurotrophic factor) production. These neurotransmitters and BDNF create an intelligent neurotransmitter recycling system to amplify each other's mind and mood-boosting potential. Increased BDNF expression revives neurotransmitter activity, waking them up so they can continue to enhance feelings of happiness, calm, and brain connectivity, while increased neurotransmitter activity enhances BDNF gene expression.

Inside Brain Stack Microdose Mushroom Capsules

Organic Cinnamon

Form: Ground powder, certified Canadian Organic , USDA Organic, and Ecocert Canada.

Benefit: Studied to improve attention and memory, reduce fatigue, decrease inflammation and oxidative stress, increase brain blood circulation, and advance tissue regeneration.

Organic Lion's Mane

Form: Patented extraction from certified organic Lion's Mane fruiting bodies, standardized to >25% 1,3 and 1,6 beta-glucans.

Benefit: Known to be neuroprotective and repair nerve damage. Studied to enhance mood, decrease anxiety and improve cognition, sleep quality, and immunity.. Studied to enhance mood, decrease anxiety and improves sleep quality, cognition, and immunity.

Organic Psilocybe cubensis

Form: Ground powder made from 100% fruiting body.

Benefit: Promotes neurogenesis, synaptogenesis, and neuroplasticity. Activates serotonin receptors responsible for mood, learning, and memory consolidation. Treats anxiety and combats depression.

Organic Sage

Form: 4:1 patented concentrated extract ensures bioavailability.

Benefit: Shown to enhance cognitive skills, guard against neurodegenerative disorders, and increase alertness.

Vitamin B3 (as Niacin)

Form: Bioactive and bioavailable, 100% pure and naturally-derived.

Benefit: Helps convert fat, protein, and carbs into energy.

My Supply Co. Unstress Stacks - Daily Brain Health - Full Spectrum CBD and Brain Stack Microdose Capsules

Bye bye brain fog.

Stress and brain health are entangled. Brain Stack and Full Spec. CBD deliver critical nutrients to help manage stress while promoting healthy brain function.

Starting at ▸ $59

Frequently Asked Questions

How does Brain Stack work?

Stress, depression, toxins, and oxidative stress deplete vital brain chemistry and prematurely shrink your brain, leading to brain fog, poor memory, irritability, anxiety, and more. Brain Stack, a brain supplement, is our master nootropic formula that's clinically shown to help restore vital brain chemistry and functional brain connectivity and promote memory, concentration, mood, and brain vitality.

Brain Stack microdose capsules have Psilocybin, Lion's Mane, Cinnamon, Sage, and Vitamin B3 to create an intelligent neurotransmitter recycling system. Psilocybin and Lion's Mane modulate monoamine neurotransmitters like serotonin, dopamine, and norepinephrine to help wake the mind and mood, improve your ability to adapt to stress, and enhance BDNF (brain-derived neurotrophic factor) production. BDNF in turn promotes the survival and differentiation of serotonin and dopamine neurons so they're able to continue supporting vital brain chemistry and enhance functional brain connectivity.

Vitamin B3 helps convert fat, carbs, and protein into cellular energy/ATP while supporting healthy serotonin production.

Cinnamon and Sage deliver a potent antioxidant complex to protect the brain from inflammation and oxidative stress.

How does Brain stack support vital brain chemistry and functional brain connectivity?

BDNF and serotonin are seemingly distinct signaling systems that play regulatory roles in many neuronal functions including survival, neurogenesis, and synaptic plasticity. An imbalance of one typically results in an imbalance of the other, leading to anxiety, depression, and other mood disorders.

In pre-clinical trials, Lion's Mane completely reversed stress- and depression-induced low levels of norepinephrine, dopamine, serotonin, and BDNF in the hippocampus.

Psilocybin is shown to have a similar effect on serotonin, dopamine, and BDNF in the pre-frontal cortex (PFC).

Together, Psilocybin and Lion's Mane in Brain Stack support healthy neurotransmitter signaling and BDNF expression in both the PFC and Hippocampus — improving memory, promoting focus, and enhancing your ability to adapt to and overcome stress.

Is Brain Stack clinically tested?

No, Brain Stack as a product is not clinically tested. The ingredients themselves have been clinically tested through the monumental effort of scientists and specialists around the world.

We formulated Brain Stack based on their demonstrated benefits and effects to create a master nootropic supplement for complete proactive + reactive brain health.

Is Brain Stack vegan?

Yes! All of our Stacks are vegan and tested for pesticides, heavy metals, microbiological content, and more.

What is the difference between Brain Stack, Energy Stack, and Immune Stack? They both have Psilocybin, right?

Think of Brain Stack, a microdose supplement, as a master nootropic complex for proactive + reactive brain health, think of Energy Stack as an energy-multiplying supplement, and think of Immune Stack as a potent antioxidant complex for cell health plus mushroom magic.

They all have 25mg Psilocybe cubensis per capsule, and confer the mind and mood-boosting benefits of Psilocybin.

Can I take all the Stacks together?

Yes, in fact, we recommend it. All of our products are formulated in doses designed to be taken together. We recommend taking them in the AM.

+ Brain Stack is proactive + reactive brain health for mood, memory, and concentration
+ Energy Stack is your non-stim wakeup call for boosting energy, metabolism, and mood
+ Immune Stack is restorative cellular care for your brain, sex, hair, skin, recovery, and immune goals

Customer Reviews
4.8 Based on 29 Reviews
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I recommend this product

Super stack!

Makes me feel focused, calm and alert. I feel ready to take on whatever the day bring. Highly recommend!

  • Wellness Concern: MoodEnergy
  • Age Range: 25 - 34
I recommend this product


I have seen an incredible difference in my mood and anxiety since starting the Brain Stack. I find that I am much more positive throughout the day and do not get anxious over little things like I did before. I also find that my focus has improved a lot as well. I practise the 4 days on and 3 days off and take 2 brain stacks and 1 energy stack in the morning. When you first start microdosing you won’t feel obvious/ outwardly effects but as you continue using them, you will start to see a difference in your overall well-being/demeanour and how you approach your day to day life. I would recommend the brain stack to anyone!!

  • Wellness Concern: AnxietySleepMoodEnergyFocus
  • Age Range: 25 - 34
Kevin C.
I recommend this product

Brainstack review

Taking these have increased my energy and mood. Being in a good mood is less of a struggle after taking these in the morning. It makes me feel more focused and alert too.

  • Which benefits or effects did you experience? (Choose as many as you like) Appreciating life moreIncreased creativityMore calm and adaptable to stressDecreased anxietyDecreased depressionA sense of peace or wellbeing
  • Wellness Concern (Choose as many as you like) AnxietyMoodEnergy
  • Age Range (Optional) 35 - 44
My Supply Co. Brain Stack Microdose Mushroom Capsules ReviewMy Supply Co. Brain Stack Microdose Mushroom Capsules Review
I recommend this product

Allowed me to kick my ADHD meds to the curb!

These Brain Stack mushroom capsules have been life changing for my ADHD. Previously I was prescribed two different kinds of medication to manage my ADHD and I didn't like the side effects, and prefer to go a more natural route. Not only did I not have to go through painful adjustments of taking new meds and finding the right dosage, I also immediately noticed the positive effects of these capsules without having to have them build up in my system or allow my body to adjust. Within the first week of taking them I was working on my phone with my kids running all around me like crazy. Then it hit me, previously to taking these capsules I would have never been able to handle that situation without being way overstimulated, getting frustrated, and not being able to focus. Instead I was able to put my focus on my phone and get done what I needed to, and my kids could play around me just like kids should be able to do. I've been taking them for 6ish months at this point and will never go back. Not only has my focus improved, but so has my mood. And for anyone worried about being "high" and your ability to do normal day to day things, 1st, that worry is totally valid, and 2nd, you really don't need to worry about it at all because there is no incapacitation. I waited to take my first dose for a low key weekend day when my husband was home, and after that I saw how not of a thing it was, and continue to take them 4ish days a week and can work, do school drop offs, and all the other things a working mom needs to do. I highly highly recommend trying Brain Stack.

  • Benefits Experienced: Appreciating life moreIncreased creativityMore calm and adaptable to stressImproved cognitionDecreased anxietyDecreased depressionA sense of peace or wellbeing
  • Wellness Concern: AnxietyFocus
  • Age Range (Optional) 25 - 34
I recommend this product

Some days I feel a difference.

Some days it makes a difference, some days it doesn't. When it does, it makes a huge difference.

  • Which benefits or effects did you experience? (Choose as many as you like) Appreciating life moreDecreased anxietyDecreased depression
  • Wellness Concern (Choose as many as you like) Mood
  • Age Range (Optional) 25 - 34

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