Psilocybin Microdosing Capsules

Frequently Asked Questions

What is Psilocybin microdosing?

Psilocybin microdosing involves taking sub-hallucinogenic doses of psilocybin, the active compound found in magic mushroom species like Psilocybe cubensis. While it is frequently and erroneously referred to as "sub-perceptual," the goal is to achieve perceptual benefits that are below the hallucinogenic threshold, including:

  • enhancing mood, emotional regulation, and emotional processing
  • improving cognition and memory
  • sharpening acuity, focus
  • increasing creative, divergent, and outside-the-box thinking

All without mental impairment or hallucinations.

What are the benefits of microdosing Psilocybin?

Microdosing Psilocybin, which involves taking sub-hallucinogenic doses, may have several significant benefits. According to various studies and anecdotal reports, microdosing may enhance cognitive flexibility, creativity, and problem-solving abilities by improving both convergent and divergent thinking. It’s also associated with improved mood and mental health, with many individuals experiencing a decline in anxiety, depression, ADHD, burnout, fear, and stress.

Here's a summary of the undesirable states that microdosing reduces:

Microdosing psilocybin also increases several desirable states, particularly in cognitive and emotional well-being. These include:

  • Enhanced Creativity: An increase in the ability to generate new ideas and perspectives.

  • Improved Focus and Concentration: Better attention to tasks and improved productivity.

  • Emotional Stability: Greater emotional balance and resilience.

  • Openness: Increased openness to new experiences and perspectives.

  • Well-being: A general sense of improved well-being and life satisfaction.

How should I take Psilocybin microdosing capsules?

We recommend starting with 1-4 capsules, depending on your tolerance and desired effects.

If you want to learn how to take your Psilocybin microdosing capsules like a pro, follow these expert tips:

  • Consuming psilocybin capsules on an empty stomach may speed up absorption and onset time.

  • A light pre-mushroom snack can reduce nausea and enhance the experience.

  • Shroom tea and lemon tek can mask the flavor and improve absorption.

  • Eating before taking Psilocybin capsules may slow the onset of effects and reduce the trip's intensity or duration.

  • If you choose to eat, opt for light, easily digestible foods before taking your Psilocybin capsules.

  • Chitin in mushrooms is believed to cause nausea.

  • Find what works best for you when it comes to eating and taking shrooms. Journaling helps you keep track of your dosages and the effects you're experiencing as you go along. Consistency and patience are key.

How often should I microdose Psilocybin?

There are studied and established protocols that you can follow to maximize the benefits you get from microdosing, without building a tolerance. Each microdosing protocol follows a specific schedule for a specific amount of time, and while all of them are different, they all have one thing in common:

They all take small breaks between microdosing days, followed by longer days to reset your tolerance.

Two popular microdosing protocols are the Stamets protocol and the Fadiman protocol. The Stamets protocol involves taking one day of microdosing Psilocybin followed by a two-day break. Instead, the Fadiman protocol suggests microdosing for 5 days, followed by a 2-day break.

It's essential to find the protocol that works best for your body and goals through experimentation. To start microdosing like a pro, we recommend reading our guide to microdosing protocols, schedules, and cycles. You'll learn about 7 different protocols and the exact rationale behind each.

What are the risks and side effects of microdosing Psilocybin?

Psilocybin is one of the safest "drugs" known—safer than cannabis, tobacco, and alcohol, as demonstrated by the chart below:

Overall weighted harm scores for different drugs, ranking them from most harmful to least harmful. Harm criteria include mortality, damage, dependence, harm to self, harm to others, environmental damage, international damage, economic cost, etc. Psilocybin mushrooms are the least harmful, while alcohol, heroin, and crack cocaine are the most harmful, respectively.

Source: Drug harms in the UK: A multi-criterion decision analysis

However, and despite its safety profile, you might experience side effects such as nausea, headache, restlessness, or mild anxiety. It's important to start with low doses and monitor how your body reacts.

As always, you can chat with us if you need help crafting your protocol. If we cannot help you, we can help put you in touch with a professional that can.

Can I combine My Supply Co.'s Psilocybin microdosing capsules with other supplements or medications?

Yes! Our microdosing capsules are formulated with powerful nootropics, adaptogens, and clinical-level actives to help your body more effectively regulate its own biochemistry and restore homeostatic balance. This practice of combining Psilocybin mushrooms with other ingredients is called stacking, and has been done for thousands of years and clinically affirmed by modern science to work synergistically to produce more profound shifts in your health and well-being.

However, these herbs are powerful medicines, and you should speak to your healthcare practitioner, nutrition expert, naturopathic doctor, or psychedelic-assisted therapist before making changes to your health regimen.

How long does it take to feel the effects of Psilocybin microdose capsules?

You will experience different effects at different stages of your Psilocybin microdosing practice:

  • Immediate Effects: At the beginning you may feel immediate sub-hallucinogenic effects, such as better mood, emotional stability, sharper focus, more clarity, increased creativity and acuity, and more out of the box thinking.

  • Accumulating Effects:Over time, you will begin to notice an increase in your energy levels, mental stamina, and memory. You will also experience less sensitivity to stress, become more mentally flexible, and adapt more easily to new situations and challenges. You may also experience less anxiety, depression, and more social confidence.

However, your chemistry is unique to you. Some individuals report feeling effects within a few days, while others may take longer to experience benefits. Consistency is key.

What immediate effects can I expect from Psilocybin microdosing capsules?

Initially, you may experience sub-hallucinogenic effects that enhance mood, emotional stability, and mental clarity. There’s also a potential for sharper focus, increased creativity, and more innovative thinking.

How will Psilocybin microdosing affect my energy and mental stamina over time?

You may experience increased energy levels, improved mental stamina, and enhanced memory. This gradual change can contribute to overall well-being and cognitive function.

Can Psilocybin microdosing lead to changes in stress response and adaptability?

With continued practice, microdosing Psilocybin helps ease your sensitivity to stress. You might find yourself becoming more mentally flexible and better able to adapt to new situations and challenges.

What are the long-term mental health benefits of microdosing Psilocybin?

Long-term, the symptoms of anxiety and depression ease, and you experience a gradual shift in your social confidence. However, it’s important to note that the long-term effects are not fully understood, and more research is needed.

Who is microdosing Psilocybin NOT suitable for?

Microdosing psilocybin is not suitable for certain individuals due to the potential risks and contraindications. Here are some groups for whom microdosing psilocybin may not be appropriate:

  • Pregnant Individuals: Psilocybin can affect fetal development, so it is contraindicated during pregnancy.

  • People with Seizure Disorders: Those with epilepsy or other seizure disorders should avoid psilocybin due to the risk of exacerbating their condition.

  • Individuals with Severe Cardiovascular Disease: Psilocybin can elevate blood pressure and heart rate, which can be dangerous for people with uncontrolled blood pressure, heart failure, coronary artery disease, or a history of heart attack or stroke.

  • Those on Certain Medications: There is virtually zero risk of getting Serotonin Syndrome (SS) from Psilocybin alone; science has yet to discover a dose that can cause it. However, combining medications that increase serotonin levels, such MAO-I or Lithium antidepressants may lead to fatal SS, especially if you have not or cannot be weaned off these medications before treatment.

It’s important to consult with a healthcare professional before starting any form of self-medication, including microdosing Psilocybin, to ensure safety and proper guidance.

Can Psilocybin microdosing help with depression?

Yes. There is strong clinical and anecdotal evidence that Psilocybin, especially when combined with supportive psychotherapy, may have long-lasting antidepressant effects. A study by Johns Hopkins Medicine found that two doses of psilocybin could ease symptoms of major depressive disorder for up to a year in some patients. This suggests that psilocybin-assisted therapy might offer significant improvements in depression.

Can Psilocybin microdosing help with anxiety?

Microdosing psilocybin has been associated with improved mood and a decline in anxiety. A large study showed that individuals who microdose psilocybin experienced greater improvements in mental health and mood over a one-month period compared to those who did not microdose. This points to the potential of psilocybin in alleviating symptoms of anxiety.

Can Psilocybin microdosing help with PTSD?

Psychedelic medicines like Psilocybin are being explored as potential treatments for PTSD due to their ability to induce brain plasticity and modify connectivity between brain regions. Studies suggest that psilocybin, especially in microdoses, may help increase stress resiliency and reduce compulsive behaviors, which are often associated with PTSD.

Can Psilocybin microdosing help with ADHD?

While research is still in the early stages, there is growing interest in microdosing psychedelics like psilocybin as an alternative to traditional stimulant medications for ADHD. Anecdotal evidence and preliminary studies suggest that microdosing Psilocybin may improve focus and cognitive function, which could be beneficial for individuals with ADHD.

Can Psilocybin microdosing help with OCD?

Microdosing psilocybin may also be beneficial for treating symptoms of OCD. A 2024 study is aiming to investigate the effects of oral psilocybin on OCD symptomatology and explore the neural mechanisms that may mediate its therapeutic effects. This could lead to new treatment avenues for those suffering from OCD.

Can Psilocybin microdosing help with age-related cognitive decline?

Psilocybin has both neuroprotective and neuroregenerative properties that increase your health span by helping your brain age stronger than your non-microdosing peers.

Here is a summary of its different mechanisms of action:

  • BDNF (Brain-Derived Neurotrophic Factor): Psilocybin has been shown to increase the production of BDNF, which plays a critical role in brain health by promoting the survival of existing neurons and encouraging the growth of new neurons and synapses.

  • Glutamate Modulation: Psilocybin can modulate glutamate levels, which is important because glutamate is a major neurotransmitter associated with learning and memory. Proper regulation of glutamate can help maintain optimal cognitive function.

  • Healthy Serotonin Activity: Psilocybin is known to interact with serotonin receptors in the brain. Healthy serotonin activity is associated with mood regulation, and this interaction might also contribute to cognitive benefits.

  • Neurogenesis and Neuroplasticity: Psilocybin significantly increases neurogenesis (the growth of new brain cells) and neuroplasticity (the brain’s ability to reorganize itself by forming new neural connections), which are vital for learning and memory.

  • Reduces Neuroinflammation: Chronic inflammation in the brain is linked to cognitive decline. Psilocybin has been observed to have anti-inflammatory effects, which might help protect against age-related cognitive impairments.

Is microdosing Psilocybin addictive?

Quite the contrary—research published in the Journal of Psychopharmacology in 2022 states that "Psilocybin has a low toxicity, is non-addictive and has been shown to predict favourable changes in patients with depression, anxiety and other conditions marked by rigid behavioural patterns, including substance (mis)use.

The chart below summarizes the dependence and risk of Psilocybin mushrooms compared to other drugs, including nicotine, caffeine, and LSD.

Chart of dependence potential and effective dose/lethal dose ratio of several psychoactive drugs

Chart of dependence potential and effective dose/lethal dose ratio of several psychoactive drugs.

How to best store Psilocybin microdosing capsules?

To best store psilocybin capsules, you should keep them in an airtight container to protect them from moisture, which can degrade the psilocybin and encourage mold growth. It’s also important to store them in a cool, dark place to prevent heat and light from affecting their potency. Using desiccants, like silica gel packs, can help absorb any residual moisture and keep the capsules dry. Avoid freezing the capsules, as this can damage the compounds. Following these storage practices will help maintain the safety and efficacy of your Psilocybin capsules.

How do I get the most out of my Psilocybin microdosing practice?

Microdosing is a personal journey, and getting the most out of it is a matter of putting in the work to reinforce the neural pathways being created. Here are some general tips that might help:

  • Set Clear Intentions: Before you begin, clarify why you’re microdosing. Whether it’s for creativity, productivity, or personal growth, having a clear goal can guide your experience.

  • Start Low, Go Slow: Begin with a very low dose to understand how your body reacts, and gradually adjust as needed.

  • Track Your Experience: Keep a journal to note any changes in mood, cognition, or physical sensations. This can help you fine-tune your practice.

  • Integration: Actively apply any insights or enhancements you notice in your daily life.

  • Consult a Professional: If possible, seek guidance from a healthcare professional, psychedelic-assisted therapist, or a microdosing coach, especially if you’re using it for therapeutic purposes.

Remember, while many users report benefits such as improved mood, focus, and creativity, it’s important to approach microdosing with caution as it’s not suitable for everyone. Always prioritize your well-being.

Read: How To Integrate A Psychedelic Journey: 6 Post-Dose Care Tips

What strains are your Psilocybin microdosing capsules made with?

Our microdosing capsules are formulated with Golden Teachers, a Psilocybe cubensis variety that's popular with psychonauts around the world for its gentle yet potent journey, which are marked by euphoria, introspection, and visuals. We choose Golden Teachers because they offer the most consistent Psilocybin concentrations, although there are hundreds of Psilocybin-containing mushroom species, including Liberty Caps, Penis Envy, Mazatapec, Blue Meanies, and more.